RAMAN: SENTERRA II

Overview
Applications

Straightforward Raman Microscopy

The SENTERRA II defines a new level of spectroscopic performance and user friendliness in the class of compact Raman microscopes.

SENTERRA II is designed to deliver excellent sensitivity combined with high spectral and Raman Imaging performance. Therefore the SENTERRA II is a powerful platform for advanced research applications. Due to its high degree of automation, compact size and efficient workflow the SENTERRA II is likewise an ideal tool for solving real world tasks in the quality control laboratory.

Its unprecedented permanent stability of the wavenumber axis guarantees precise and accurate results at every time. The SENTERRA II is THE Raman microscope for both, the multi-user environment with high daily throughput and for the lab working at the forefront of scientific research.

SENTERRA II highlights:

Research-grade spectroscopic performance
Intuitive & convenient workflow due to software guidance and automated hardware
Unmatched wavenumber accuracy and precision by SureCAL^TM
Straightforward Raman imaging
Compact design with spectrometer included in the microscope
Full spectral range with all gratings
Multi laser excitation with fast switching capabilities
Combination with FT-Raman technology for minimized fluorescence
Fully automated instrument tests according to USP 1120, PhEur 2.2.48, ASTM E1840 and E2529-06
Full compliance with GMP/cGMP, GLP and 21 CFRp11
Open architecture version for the study of larger samples (e.g. in art) with high lateral resolution

Applications of SENTERRA II

The SENTERRA II allows measuring Raman images and combines the obtained spatially resolved molecular information with high-quality microscopic images of the sample. The analysis is performed contactless and without the need of sample preparation. Chemical images of the sample surface can be achieved with a very high spatial resolution down to less than a micron. In addition depth profiling of optically transparent samples allows non-destructive sample investigation in the third dimension. Being suitable to be used for the detection, discrimination and identification of organic and inorganic materials the SENTERRA II has a wide range of applications.

Polymers

Identification of pure polymers and blends
Analysis of multilayer systems
Characterization of polymers: crystallinity, density, conformation
Determination of monomer content, fillers, additives
Failure analysis: identification of impurities and inclusions

Pharmaceutical

Differentiation of polymorphs
Visualization of the distribution of API and excipients in tablets
Failure analysis: Identification of particles & inclusions

Materials Science

Differentiation of amorphous and microcrystalline silicon
Characterization of novel 2D materials & carbon nanotube

Forensics

Identification of trace evidence from crime scenes such as fibers, particles, paint chips, etc.
Proof of the authenticity of works of art
Analysis of counterfeit documents, pharmaceuticals and money
Illicit drug analysis

Art and Cultural Heritage

Identification of materials used for art objects
Discrimination of genuine and fake artifacts
Study of preservation, degradation and aging of objects of art

Life Science

Study of the molecular composition of cells and tissue

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Analysis of Microplastics using FTIR and Raman-Microscopy

FT-IR microscopy has established itself as the standard method for the analysis of MPP; it can be applied universally and enables a secure identification of all polymer types. Mapping measurements or FPA imaging allows determining thousands of MPPs in a fully automated manner.

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